Nigella sativa Pretreatment in Guinea Pigs Exposed to Cigarette Smoke Modulates In Vitro Tracheal Responsiveness
نویسندگان
چکیده
منابع مشابه
nigella sativa pretreatment in guinea pigs exposed to cigarette smoke modulates in vitro tracheal responsiveness
conclusions these results showed the preventive effect of hydroethanolic extract of n. sativa on tracheal responsiveness of guinea pig model of copd, which was as effective as vitamin c. results the tracheal responsiveness to both methacholine and ovalbumin in guinea pigs with copd were significantly higher than those of controls (p < 0.001 for both cases). the tracheal responsiveness in the co...
متن کاملNigella sativa Pretreatment in Guinea Pigs Exposed to Cigarette Smoke Modulates In Vitro Tracheal Responsiveness
BACKGROUND In previous studies, the bronchodilator and antitussive effects of Nigella sativa have been demonstrated on guinea pigs. OBJECTIVES In the present study, the effect of the hydroethanolic extract of N. sativa on tracheal responsiveness in guinea pigs exposed to cigarette smoke was examined. MATERIALS AND METHODS Three groups of guinea pig models of COPD were given drinking water a...
متن کاملThe effect of Nigella sativa extract on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs
OBJECTIVE To examine the preventive effect of a hydro-ethanolic extract of Nigella sativa on the tracheal responsiveness and white blood cell count in the lung lavage fluid of sensitized guinea pigs. METHODS Three groups of guinea pigs sensitized to intraperitoneally injected and inhaled ovalbumin were given drinking water alone (group S), drinking water containing a low concentration of N. s...
متن کاملThymoquinone, the main constituent of Nigella sativa, affects adenosine receptors in asthmatic guinea pigs
Objective(s): For determining the mechanism of anti-asthmatic effect of thymoquinone, this investigation evaluated the effect of thymoquinone in the presence of selective A2A and A2B adenosine receptor antagonists (ZM241385 and MRS1706, respectively). Materials and Methods: Seventy guinea pigs were randomly divided to 7 groups; control (C), sensitized with ovalbumin (S), sensitized groups pretr...
متن کاملTracheal responsiveness to methacholine and ovalbumin; and lung inflammation in guinea pigs exposed to inhaled lead after sensitization.
The association between lead exposure and asthma is controversial. The effect of inhaled lead acetate on lung inflammation, tracheal responsiveness and immune components in guinea pigs after sensitization was examined in this study. Five groups of guinea pigs were randomly allocated to control (group C), sensitized (group S), and three test groups exposed to inhaled lead concentrations 0.1, 0.2...
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ژورنال
عنوان ژورنال: Iranian Red Crescent Medical Journal
سال: 2014
ISSN: 2074-1804,2074-1812
DOI: 10.5812/ircmj.10421